,
Angelica Maria Mendoza Caballero*,
Emanuel Alexis Troncoso Villadiego,
Richard Romero Ruiz,
Adolfo Álvarez Montañez
Acute necrotizing encephalopathy is a rapidly progressive disease of the central nervous system that is generally described in texts as a pathology of pediatric patients, but even in people of this age range, it is rare to find a case of this disease, which presents with a fulminant tissue necrosis and can be secondary to infections, mainly of viral origin. Due to presenting very non-specific clinical manifestations, this diagnosis often goes unnoticed or is made late. ANE survivors go through three phases during the clinical course that include the prodromal stage, the period of acute encephalopathy, and the recovery stage. It is through specific radiological findings observed on computed tomography affecting the bilateral thalamus and possibly the cerebral white matter, brainstem, or cerebellum that the diagnosis can be confirmed. This report discusses the case of an 8-year-old schoolboy who begins with acute gastroenteritis, which progresses with seizures and neurological deterioration. A skull CT scan is performed with imaging findings suggestive of acute necrotizing encephalopathy. Management is established with adequate clinical response and favorable recovery of neurological symptoms. The clinical characteristics and radiological findings are the key to facilitating an early diagnosis, reducing sequelae and improving the prognosis, which provides a chance of life to people who suffer from this condition.
| Published in | American Journal of Pediatrics (Volume 10, Issue 3) |
| DOI | 10.11648/j.ajp.20241003.12 |
| Page(s) | 117-122 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Encephalopathy, Virus, Seizure, Neuroimaging
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APA Style
Algarín, R. A. S., Caballero, A. M. M., Villadiego, E. A. T., Ruiz, R. R., Montañez, A. Á. (2024). Acute Necrotizing Encephalopathy in Children: A Case Report in Barranquilla-Colombia. American Journal of Pediatrics, 10(3), 117-122. https://doi.org/10.11648/j.ajp.20241003.12
ACS Style
Algarín, R. A. S.; Caballero, A. M. M.; Villadiego, E. A. T.; Ruiz, R. R.; Montañez, A. Á. Acute Necrotizing Encephalopathy in Children: A Case Report in Barranquilla-Colombia. Am. J. Pediatr. 2024, 10(3), 117-122. doi: 10.11648/j.ajp.20241003.12
AMA Style
Algarín RAS, Caballero AMM, Villadiego EAT, Ruiz RR, Montañez AÁ. Acute Necrotizing Encephalopathy in Children: A Case Report in Barranquilla-Colombia. Am J Pediatr. 2024;10(3):117-122. doi: 10.11648/j.ajp.20241003.12
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Download@article{10.11648/j.ajp.20241003.12,
author = {Ricardo Andrés Sánchez Algarín and Angelica Maria Mendoza Caballero and Emanuel Alexis Troncoso Villadiego and Richard Romero Ruiz and Adolfo Álvarez Montañez},
title = {Acute Necrotizing Encephalopathy in Children: A Case Report in Barranquilla-Colombia
},
journal = {American Journal of Pediatrics},
volume = {10},
number = {3},
pages = {117-122},
doi = {10.11648/j.ajp.20241003.12},
url = {https://doi.org/10.11648/j.ajp.20241003.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20241003.12},
abstract = {Acute necrotizing encephalopathy is a rapidly progressive disease of the central nervous system that is generally described in texts as a pathology of pediatric patients, but even in people of this age range, it is rare to find a case of this disease, which presents with a fulminant tissue necrosis and can be secondary to infections, mainly of viral origin. Due to presenting very non-specific clinical manifestations, this diagnosis often goes unnoticed or is made late. ANE survivors go through three phases during the clinical course that include the prodromal stage, the period of acute encephalopathy, and the recovery stage. It is through specific radiological findings observed on computed tomography affecting the bilateral thalamus and possibly the cerebral white matter, brainstem, or cerebellum that the diagnosis can be confirmed. This report discusses the case of an 8-year-old schoolboy who begins with acute gastroenteritis, which progresses with seizures and neurological deterioration. A skull CT scan is performed with imaging findings suggestive of acute necrotizing encephalopathy. Management is established with adequate clinical response and favorable recovery of neurological symptoms. The clinical characteristics and radiological findings are the key to facilitating an early diagnosis, reducing sequelae and improving the prognosis, which provides a chance of life to people who suffer from this condition.
},
year = {2024}
}
TY - JOUR T1 - Acute Necrotizing Encephalopathy in Children: A Case Report in Barranquilla-Colombia AU - Ricardo Andrés Sánchez Algarín AU - Angelica Maria Mendoza Caballero AU - Emanuel Alexis Troncoso Villadiego AU - Richard Romero Ruiz AU - Adolfo Álvarez Montañez Y1 - 2024/07/23 PY - 2024 N1 - https://doi.org/10.11648/j.ajp.20241003.12 DO - 10.11648/j.ajp.20241003.12 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 117 EP - 122 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20241003.12 AB - Acute necrotizing encephalopathy is a rapidly progressive disease of the central nervous system that is generally described in texts as a pathology of pediatric patients, but even in people of this age range, it is rare to find a case of this disease, which presents with a fulminant tissue necrosis and can be secondary to infections, mainly of viral origin. Due to presenting very non-specific clinical manifestations, this diagnosis often goes unnoticed or is made late. ANE survivors go through three phases during the clinical course that include the prodromal stage, the period of acute encephalopathy, and the recovery stage. It is through specific radiological findings observed on computed tomography affecting the bilateral thalamus and possibly the cerebral white matter, brainstem, or cerebellum that the diagnosis can be confirmed. This report discusses the case of an 8-year-old schoolboy who begins with acute gastroenteritis, which progresses with seizures and neurological deterioration. A skull CT scan is performed with imaging findings suggestive of acute necrotizing encephalopathy. Management is established with adequate clinical response and favorable recovery of neurological symptoms. The clinical characteristics and radiological findings are the key to facilitating an early diagnosis, reducing sequelae and improving the prognosis, which provides a chance of life to people who suffer from this condition. VL - 10 IS - 3 ER -
Pediatrics Department, Pediatric Specialized Care Center, Barranquilla, Colombia
Pediatrics Department, Pediatric Specialized Care Center, Barranquilla, Colombia
Pediatrics Department, Pediatric Specialized Care Center, Barranquilla, Colombia
Pediatric Intensive Care Units, Specialized Care Center, Barranquilla, Colombia
Pediatric Neurology Department, Pediatric Specialized Care Center, Barranquilla, Colombia
