The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases

Ilham Bouarab; Fatima Zahra Yakine; Salma Tyhami; Fatim Zahra Alaoui Inboui; Bouchra Slaoui

doi:doi:10.11648/j.ajp.20241003.18

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The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases

Ilham Bouarab^*, Fatima Zahra Yakine, Salma Tyhami, Fatim Zahra Alaoui Inboui, Bouchra Slaoui

Published in American Journal of Pediatrics (Volume 10, Issue 3)

Received: 7 July 2024 Accepted: 9 August 2024 Published: 27 August 2024

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Abstract

The combination of pulmonary tuberculosis and type 1 diabetes is a significant public health problem, especially in developing countries, where the incidence of both diseases is rising sharply. According to the World Health Organization (WHO), by 2022, 23% of tuberculosis cases will be in Africa. Morocco is one of the countries with a medium incidence of tuberculosis. The Ministry of Health has launched a national strategic plan for the prevention and control of tuberculosis. However, there is no national study on the prevalence of tuberculosis in diabetic children in Morocco. Several studies in the literature have investigated the specifics of this association, and have shown that there is a two-way association between tuberculosis and type 1 diabetes. Latent tuberculosis is most common in diabetic children, while active tuberculosis can give rise to severe and atypical presentations. In this study 2 cases have been reported of type 1 diabetes associated with pulmonary tuberculosis, of varying severity, in a 15-year-old child known to be diabetic and an 18-month-old infant with inaugural diabetes, in order to determine the clinical, paraclinical, therapeutic and evolutionary particularities of tuberculosis in these children.

Published in	American Journal of Pediatrics (Volume 10, Issue 3)
DOI	10.11648/j.ajp.20241003.18
Page(s)	152-157
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Diabetes Type 1, Pulmonary Tuberculosis, Mycobacterium Tuberculosis, Glycemic Imbalance

References

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[2]	FOE-ES, Joseph Ro, KENMOE. Diabetes mellitus and tuberculosis, a systematic review and meta-analysis with sensitivity analysis for studies comparable for confounders. PLoS One, 2021, vol. 16, no 12, p. e0261246. https://doi.org/10.1371/journal.pone.0261246
[3]	HADJI, W., AMAR, A., ZADOUK, H.. P139 Les particularités de la tuberculose pulmonaire chez les diabètiques [The particularities of pulmonary tuberculosis in diabetics]. Diabetes & Metabolism, 2012, vol. 38, p. A64. https://doi.org/10.1016/S1262-3636(12)71241-7
[4]	Majaliwa ES, Muze K, Godfrey E, Latent tuberculosis in children and youth with type 1 diabetes mellitus in Dar es Salaam, Tanzania: a cross section survey. BMC Infect Dis. 2023 Oct 3 23) 23(1): 740. https://doi.org/10.1186/s12879-023-08753-40
[5]	PLAN STRATÉGIQUE NATIONAL POUR LA PRÉVENTION ET LE CONTRÔLE DE LA TUBERCULOSE AU MAROC 2024-2030. [NATIONAL STRATEGIC PLAN FOR THE PREVENTION AND CONTROL OF TUBERCULOSIS IN MOROCCO 2024-2030 Page 15. URL https://www.sante.gov.ma (accessed 06 july 2024)
[6]	Hayashi S, Chandramohan D. Risk of active tuberculosis among people with diabetes mellitus: systematic review and meta-analysis. Trop Med Int Health. 2018 Oct; 23(10): 105.1070. https://doi.org/10.1111/tmi.13133
[7]	Casqueiro J, Alves C. Infections in patients with diabetes mellitus: A review of pathogenesis. Indian J Endocrinol Metab. 2012 Mar; 16 Suppl 1(Suppl1): S27-36. https://doi.org/10.4103/2230-8210.94253
[8]	SHIN HJ, KIM, TO, OH HJ. Impact of diabetes mellitus on in determinate results of the QuantiFERON TB Gold In-Tube test: A propensity score matching analysis. PLoS One, 2017, vol. 12, no 7, p. e0181887. https://doi.org/10.1371/journal.pone.0181887
[9]	Walsh MC, Camerlin AJ, Miles R. The sensitivity of interferon-gamma release assays is not compromised in tuberculosis patients with diabetes. Int J Tuberc Lung Dis. 2011 Feb; 15(2): 179-84.
[10]	FAURHOLT J, Daniel A, Martine G, et al. Diabetes is associated with lower tuberculosis antigen-specific interferon gamma release in Tanzanian tuberculosis patients and non-tuberculosis controls. Scandinavian journal of infectious diseases, 2014, vol. 46, no 5, p. 384-391.
[11]	Hassan H, Komba Y, Etoughe F. The contribution of the Xpert MTB / RIF test in the diagnosis and treatment of tuberculosis. Rev Mali Infect Microbiol 2021, Vol 16 N°2.
[12]	BAGAYOKO K, Samake EKZ, AHOU TD, et al. Accès universel aux tests de sensibilité aux antituberculeux: cas du GeneXpert à Abidjan [Universal access to anti-tuberculosis drug susceptibility testing: the case of GeneXpert in Abidjan]. Revue des Maladies Respiratoires Actualités, 2021, vol. 13, no 1, p. 232.
[13]	WATANABE N, SAITO K, KIRITANI A. A case of invasive pulmonary aspergillosis diagnosed by transbronchial lung biopsy during treatment for diabetic ketoacidosis in a type 1 diabetic patient. Journal of Infection and Chemotherapy, 2020, vol. 26, no 2, p. 274-278. https://doi.org/10.1016/j.jiac.2019.08.011
[14]	BLAIZE M, JABET A, PIARROUX R. Infections fongiques pulmonaires (à l’exception de la pneumocystose) [Pulmonary fungal infections (except pneumocystis)]. Revue Francophone des Laboratoires, 2024, vol. 2024, no 559, p. 51-62. https://doi.org/10.1016/S1773-035X(24)00078-9
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APA Style

Bouarab, I., Yakine, F. Z., Tyhami, S., Inboui, F. Z. A., Slaoui, B. (2024). The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases. American Journal of Pediatrics, 10(3), 152-157. https://doi.org/10.11648/j.ajp.20241003.18

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ACS Style

Bouarab, I.; Yakine, F. Z.; Tyhami, S.; Inboui, F. Z. A.; Slaoui, B. The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases. Am. J. Pediatr. 2024, 10(3), 152-157. doi: 10.11648/j.ajp.20241003.18

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AMA Style

Bouarab I, Yakine FZ, Tyhami S, Inboui FZA, Slaoui B. The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases. Am J Pediatr. 2024;10(3):152-157. doi: 10.11648/j.ajp.20241003.18

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@article{10.11648/j.ajp.20241003.18,
  author = {Ilham Bouarab and Fatima Zahra Yakine and Salma Tyhami and Fatim Zahra Alaoui Inboui and Bouchra Slaoui},
  title = {The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases
},
  journal = {American Journal of Pediatrics},
  volume = {10},
  number = {3},
  pages = {152-157},
  doi = {10.11648/j.ajp.20241003.18},
  url = {https://doi.org/10.11648/j.ajp.20241003.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20241003.18},
  abstract = {The combination of pulmonary tuberculosis and type 1 diabetes is a significant public health problem, especially in developing countries, where the incidence of both diseases is rising sharply. According to the World Health Organization (WHO), by 2022, 23% of tuberculosis cases will be in Africa. Morocco is one of the countries with a medium incidence of tuberculosis. The Ministry of Health has launched a national strategic plan for the prevention and control of tuberculosis. However, there is no national study on the prevalence of tuberculosis in diabetic children in Morocco. Several studies in the literature have investigated the specifics of this association, and have shown that there is a two-way association between tuberculosis and type 1 diabetes. Latent tuberculosis is most common in diabetic children, while active tuberculosis can give rise to severe and atypical presentations. In this study 2 cases have been reported of type 1 diabetes associated with pulmonary tuberculosis, of varying severity, in a 15-year-old child known to be diabetic and an 18-month-old infant with inaugural diabetes, in order to determine the clinical, paraclinical, therapeutic and evolutionary particularities of tuberculosis in these children.
},
 year = {2024}
}

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TY  - JOUR
T1  - The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases

AU  - Ilham Bouarab
AU  - Fatima Zahra Yakine
AU  - Salma Tyhami
AU  - Fatim Zahra Alaoui Inboui
AU  - Bouchra Slaoui
Y1  - 2024/08/27
PY  - 2024
N1  - https://doi.org/10.11648/j.ajp.20241003.18
DO  - 10.11648/j.ajp.20241003.18
T2  - American Journal of Pediatrics
JF  - American Journal of Pediatrics
JO  - American Journal of Pediatrics
SP  - 152
EP  - 157
PB  - Science Publishing Group
SN  - 2472-0909
UR  - https://doi.org/10.11648/j.ajp.20241003.18
AB  - The combination of pulmonary tuberculosis and type 1 diabetes is a significant public health problem, especially in developing countries, where the incidence of both diseases is rising sharply. According to the World Health Organization (WHO), by 2022, 23% of tuberculosis cases will be in Africa. Morocco is one of the countries with a medium incidence of tuberculosis. The Ministry of Health has launched a national strategic plan for the prevention and control of tuberculosis. However, there is no national study on the prevalence of tuberculosis in diabetic children in Morocco. Several studies in the literature have investigated the specifics of this association, and have shown that there is a two-way association between tuberculosis and type 1 diabetes. Latent tuberculosis is most common in diabetic children, while active tuberculosis can give rise to severe and atypical presentations. In this study 2 cases have been reported of type 1 diabetes associated with pulmonary tuberculosis, of varying severity, in a 15-year-old child known to be diabetic and an 18-month-old infant with inaugural diabetes, in order to determine the clinical, paraclinical, therapeutic and evolutionary particularities of tuberculosis in these children.

VL  - 10
IS  - 3
ER  -

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Author Information

Ilham Bouarab

Department of Childhood Diseases, Abderrahim Harouchi Mother-Child Hospital, Casablanca, Morocco

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Fatima Zahra Yakine

Department of Childhood Diseases, Abderrahim Harouchi Mother-Child Hospital, Casablanca, Morocco

Contact Email
Salma Tyhami

Department of Childhood Diseases, Abderrahim Harouchi Mother-Child Hospital, Casablanca, Morocco

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Fatim Zahra Alaoui Inboui

Department of Childhood Diseases, Abderrahim Harouchi Mother-Child Hospital, Casablanca, Morocco

Contact Email
Bouchra Slaoui

Department of Childhood Diseases, Abderrahim Harouchi Mother-Child Hospital, Casablanca, Morocco

Contact Email

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Plain Text BibTeX RIS

APA Style

Bouarab, I., Yakine, F. Z., Tyhami, S., Inboui, F. Z. A., Slaoui, B. (2024). The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases. American Journal of Pediatrics, 10(3), 152-157. https://doi.org/10.11648/j.ajp.20241003.18

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ACS Style

Bouarab, I.; Yakine, F. Z.; Tyhami, S.; Inboui, F. Z. A.; Slaoui, B. The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases. Am. J. Pediatr. 2024, 10(3), 152-157. doi: 10.11648/j.ajp.20241003.18

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AMA Style

Bouarab I, Yakine FZ, Tyhami S, Inboui FZA, Slaoui B. The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases. Am J Pediatr. 2024;10(3):152-157. doi: 10.11648/j.ajp.20241003.18

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@article{10.11648/j.ajp.20241003.18,
  author = {Ilham Bouarab and Fatima Zahra Yakine and Salma Tyhami and Fatim Zahra Alaoui Inboui and Bouchra Slaoui},
  title = {The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases
},
  journal = {American Journal of Pediatrics},
  volume = {10},
  number = {3},
  pages = {152-157},
  doi = {10.11648/j.ajp.20241003.18},
  url = {https://doi.org/10.11648/j.ajp.20241003.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20241003.18},
  abstract = {The combination of pulmonary tuberculosis and type 1 diabetes is a significant public health problem, especially in developing countries, where the incidence of both diseases is rising sharply. According to the World Health Organization (WHO), by 2022, 23% of tuberculosis cases will be in Africa. Morocco is one of the countries with a medium incidence of tuberculosis. The Ministry of Health has launched a national strategic plan for the prevention and control of tuberculosis. However, there is no national study on the prevalence of tuberculosis in diabetic children in Morocco. Several studies in the literature have investigated the specifics of this association, and have shown that there is a two-way association between tuberculosis and type 1 diabetes. Latent tuberculosis is most common in diabetic children, while active tuberculosis can give rise to severe and atypical presentations. In this study 2 cases have been reported of type 1 diabetes associated with pulmonary tuberculosis, of varying severity, in a 15-year-old child known to be diabetic and an 18-month-old infant with inaugural diabetes, in order to determine the clinical, paraclinical, therapeutic and evolutionary particularities of tuberculosis in these children.
},
 year = {2024}
}

Copy | Download

TY  - JOUR
T1  - The Particularities of Pulmonary Tuberculosis in Children with Type 1 Diabetes: About 2 Cases

AU  - Ilham Bouarab
AU  - Fatima Zahra Yakine
AU  - Salma Tyhami
AU  - Fatim Zahra Alaoui Inboui
AU  - Bouchra Slaoui
Y1  - 2024/08/27
PY  - 2024
N1  - https://doi.org/10.11648/j.ajp.20241003.18
DO  - 10.11648/j.ajp.20241003.18
T2  - American Journal of Pediatrics
JF  - American Journal of Pediatrics
JO  - American Journal of Pediatrics
SP  - 152
EP  - 157
PB  - Science Publishing Group
SN  - 2472-0909
UR  - https://doi.org/10.11648/j.ajp.20241003.18
AB  - The combination of pulmonary tuberculosis and type 1 diabetes is a significant public health problem, especially in developing countries, where the incidence of both diseases is rising sharply. According to the World Health Organization (WHO), by 2022, 23% of tuberculosis cases will be in Africa. Morocco is one of the countries with a medium incidence of tuberculosis. The Ministry of Health has launched a national strategic plan for the prevention and control of tuberculosis. However, there is no national study on the prevalence of tuberculosis in diabetic children in Morocco. Several studies in the literature have investigated the specifics of this association, and have shown that there is a two-way association between tuberculosis and type 1 diabetes. Latent tuberculosis is most common in diabetic children, while active tuberculosis can give rise to severe and atypical presentations. In this study 2 cases have been reported of type 1 diabetes associated with pulmonary tuberculosis, of varying severity, in a 15-year-old child known to be diabetic and an 18-month-old infant with inaugural diabetes, in order to determine the clinical, paraclinical, therapeutic and evolutionary particularities of tuberculosis in these children.

VL  - 10
IS  - 3
ER  -

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