Scurvy is all the symptoms associated with a diet deficient in ascorbic acid or vitamin C, found in fresh fruit and vegetables. Scurvy is a pathology resulting from a deep and prolonged vitamin C deficiency, which can manifest itself as a bleeding syndrome, wound healing disorders, rheumatic signs, or gum damage. If left untreated (vitamin C supplementation), the disease can be fatal. This water-soluble vitamin is neither synthesized nor stored in the body. In recent years, there has been a resurgence of this pathology due to unbalanced nutrition. Clinical presentations are deceptive and variable, with orthopedic abnormalities and a diffuse hemorrhagic syndrome secondary to a defect in collagen fiber synthesis in children. The diagnosis of scurvy is confirmed by measuring ascorbemia, which is less than 2 mg/L (5-15 mg/L or 17-94 mmol/L), and treatment is based on vitamin C supplementation at 100 to 300 mg/day until complete recovery. We report the case of a 7-year-old patient with an autistic spectrum disorder associated with epilepsy, who presented with scurvy revealed by bone involvement consisting of bone pain, a bleeding syndrome and gingival hypertrophy in context of altered general condition. The diagnosis was confirmed by a collapsed ascorbic acid level (<3 mmol/l) and progressed favorably on vitamin supplementation.
| Published in | American Journal of Pediatrics (Volume 10, Issue 2) |
| DOI | 10.11648/j.ajp.20241002.11 |
| Page(s) | 48-51 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Ascorbic Acid, Bleeding Syndrome, Scurvy, Vitamin C
| [1] | Fain, O. (2004). Carences en vitamine C. La revue de médecine interne, 25(12), 872-880. |
| [2] | Castilla, M., Carretero, J. M., Gracia Téllez, A., & Arsuaga, J. L. (2014). Evidence of rickets and/or scurvy in a complete Chalcolithic child skeleton from the El Portalón site (Sierra de Atapuerca, Spain). |
| [3] | Fain, O. (2005). Musculoskeletal manifestations of scurvy. Joint Bone Spine, 72(2), 124-128. |
| [4] | Solanki, M., Baweja, DK, Patil, SS et Shivaprakash, PK (2011). Carence en acide ascorbique: un rapport de cas. Journal of Dentistry for Children, 78 (2), 115-119. |
| [5] | Noble, J. M., Mandel, A., & Patterson, M. C. (2007). Scurvy and rickets masked by chronic neurologic illness: revisiting “psychologic malnutrition”. Pediatrics, 119(3), e783-e790. |
| [6] | Weinstein, M., Babyn, P., & Zlotkin, S. (2001). An orange a day keeps the doctor away: scurvy in the year 2000. Pediatrics, 108(3), e55-e55. |
| [7] | Brambilla, A., Pizza, C., Lasagni, D., Lachina, L., Resti, M., & Trapani, S. (2018). Pediatric scurvy: when contemporary eating habits bring back the past. Frontiers in Pediatrics, 6, 126. |
| [8] | Bacci, C., Sivolella, S., Pellegrini, J., Favero, L., & Berengo, M. (2010). A rare case of scurvy in an otherwise healthy child: diagnosis through oral signs. Pediatric dentistry, 32(7), 536-538. |
| [9] | Adewumi, A. O., Ashoor, I. F., Soares, F. M., Guelmann, M., & Novak, D. A. (2010). Eruption hematoma as a possible oral sign of infantile scurvy. Pediatric dentistry, 32(2), 151-155. |
| [10] | Hodges, RE, Baker, EM, Hood, J., SAUBERLICH, HE et March, SC (1969). Scorbut expérimental chez l'homme. L'American Journal of Clinical Nutrition, 22 (5), 535-548. |
| [11] | Khonsari, H., Grandière-Perez, L., & Caumes, E. (2005). Le scorbut n'a pas disparu: histoire d'une maladie réémergente. La Revue de médecine interne, 26(11), 885-890. |
| [12] | Allgaier, RL, Vallabh, K., et Lahri, S. (2012). Scorbut: Un diagnostic difficile avec un remède simple. Journal africain de médecine d'urgence, 2 (1), 20-23. |
| [13] | Algahtani, H. A., Abdu, A. P., Khojah, I. M., & Al-Khathaami, A. M. (2010). Inability to walk due to scurvy: a forgotten disease. Annals of Saudi medicine, 30(4), 325-328. |
| [14] | Agarwal, A., Shaharyar, A., Kumar, A., & Bhat, M. S. (2015). A swollen thigh and knee pain in a cerebral palsy child–Scurvy. Joint Bone Spine, 5(82), 369. |
| [15] | Bastida, J., Dehesa, L. A., & de la Rosa, P. (2008). Pale orange perifollicular halo as a dermatoscopic sign in scurvy. Actas dermo-sifiliograficas, 99(10), 827-828. |
| [16] | Falkenberg, A. L., Karkenny, A. J., & Sharkey, M. S. (2024). Orthopaedic Manifestations of Scurvy in an Otherwise Healthy Child from a Low Opportunity Index Neighborhood: A Case Report. JBJS Case Connector, 14(1), e23. |
| [17] | Ahmad, S. A., Al Thobiti, T. A., El Toum, M., & Al Harbi, F. (2021). Florid scurvy in an autistic child on a ketogenic diet. Pediatric Emergency Care, 37(8), e483-e484. |
| [18] | Lund, R. M., Becker, M. L., Shapiro, S., Allison, T., & Harris, J. G. (2019). Scurvy presenting with limp and weakness: a case report. BMC pediatrics, 19(1), 1-4. |
| [19] | Cole, J. A., Warthan, M. M., Hirano, S. A., Gowen Jr, C. W., & Williams, J. V. (2011). Scurvy in a 10-year-old boy. Pediatric dermatology, 28(4), 444-446. |
| [20] | Bursali, A., Gursu, S., Gursu, A., & Yildirim, T. (2009). A case of infantile scurvy treated only with vitamin C: a forgotten disease. Acta Orthopædica Belgica, 75(3), 428. |
APA Style
Satlane, S., Chahid, I., Harim, F., Atrassi, M., Bensabbahia, D., et al. (2024). Scurvy in Children: A Case Report. American Journal of Pediatrics, 10(2), 48-51. https://doi.org/10.11648/j.ajp.20241002.11
ACS Style
Satlane, S.; Chahid, I.; Harim, F.; Atrassi, M.; Bensabbahia, D., et al. Scurvy in Children: A Case Report. Am. J. Pediatr. 2024, 10(2), 48-51. doi: 10.11648/j.ajp.20241002.11
AMA Style
Satlane S, Chahid I, Harim F, Atrassi M, Bensabbahia D, et al. Scurvy in Children: A Case Report. Am J Pediatr. 2024;10(2):48-51. doi: 10.11648/j.ajp.20241002.11
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Download@article{10.11648/j.ajp.20241002.11,
author = {Siham Satlane and Imane Chahid and Fatima Harim and Meriem Atrassi and Dalal Bensabbahia and Abdelhak Abkari},
title = {Scurvy in Children: A Case Report
},
journal = {American Journal of Pediatrics},
volume = {10},
number = {2},
pages = {48-51},
doi = {10.11648/j.ajp.20241002.11},
url = {https://doi.org/10.11648/j.ajp.20241002.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20241002.11},
abstract = {Scurvy is all the symptoms associated with a diet deficient in ascorbic acid or vitamin C, found in fresh fruit and vegetables. Scurvy is a pathology resulting from a deep and prolonged vitamin C deficiency, which can manifest itself as a bleeding syndrome, wound healing disorders, rheumatic signs, or gum damage. If left untreated (vitamin C supplementation), the disease can be fatal. This water-soluble vitamin is neither synthesized nor stored in the body. In recent years, there has been a resurgence of this pathology due to unbalanced nutrition. Clinical presentations are deceptive and variable, with orthopedic abnormalities and a diffuse hemorrhagic syndrome secondary to a defect in collagen fiber synthesis in children. The diagnosis of scurvy is confirmed by measuring ascorbemia, which is less than 2 mg/L (5-15 mg/L or 17-94 mmol/L), and treatment is based on vitamin C supplementation at 100 to 300 mg/day until complete recovery. We report the case of a 7-year-old patient with an autistic spectrum disorder associated with epilepsy, who presented with scurvy revealed by bone involvement consisting of bone pain, a bleeding syndrome and gingival hypertrophy in context of altered general condition. The diagnosis was confirmed by a collapsed ascorbic acid level (<3 mmol/l) and progressed favorably on vitamin supplementation.
},
year = {2024}
}
TY - JOUR T1 - Scurvy in Children: A Case Report AU - Siham Satlane AU - Imane Chahid AU - Fatima Harim AU - Meriem Atrassi AU - Dalal Bensabbahia AU - Abdelhak Abkari Y1 - 2024/04/02 PY - 2024 N1 - https://doi.org/10.11648/j.ajp.20241002.11 DO - 10.11648/j.ajp.20241002.11 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 48 EP - 51 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20241002.11 AB - Scurvy is all the symptoms associated with a diet deficient in ascorbic acid or vitamin C, found in fresh fruit and vegetables. Scurvy is a pathology resulting from a deep and prolonged vitamin C deficiency, which can manifest itself as a bleeding syndrome, wound healing disorders, rheumatic signs, or gum damage. If left untreated (vitamin C supplementation), the disease can be fatal. This water-soluble vitamin is neither synthesized nor stored in the body. In recent years, there has been a resurgence of this pathology due to unbalanced nutrition. Clinical presentations are deceptive and variable, with orthopedic abnormalities and a diffuse hemorrhagic syndrome secondary to a defect in collagen fiber synthesis in children. The diagnosis of scurvy is confirmed by measuring ascorbemia, which is less than 2 mg/L (5-15 mg/L or 17-94 mmol/L), and treatment is based on vitamin C supplementation at 100 to 300 mg/day until complete recovery. We report the case of a 7-year-old patient with an autistic spectrum disorder associated with epilepsy, who presented with scurvy revealed by bone involvement consisting of bone pain, a bleeding syndrome and gingival hypertrophy in context of altered general condition. The diagnosis was confirmed by a collapsed ascorbic acid level (<3 mmol/l) and progressed favorably on vitamin supplementation. VL - 10 IS - 2 ER -
Neuropediatrics Unit, Pediatrics 3, Children’s Hospital A. Harouchi, Casablanca, Morocco
