Background: High-flow oxygen therapy is an ideal treatment for managing respiratory failure. It avoids orotracheal intubation; however, some patients are refractory to this treatment. The ROX Index aims to detect early failure in high-flow oxygen therapy; nevertheless, its use has been poorly studied in pediatrics. Objective: To evaluate the applicability of the ROX Index as a tool to determine the failure of high-flow oxygen therapy in pediatric patients admitted to the Roberto Gilbert Hospital. Methodology: Observational, prospective, longitudinal cohort study with a descriptive approach including 209 patients between 1 month and 17 years old who required high-flow oxygen therapy within the first 24 hours. ROX Index measurements were taken at 2, 4, 6, 12, and 24 hours with follow-up to determine the outcome. Result: A total of 209 patients meeting the inclusion criteria were obtained; 27 (12.9%) required endotracheal intubation (ETI), and 182 (87%) received high-flow oxygen therapy (HFNC). A higher frequency of younger infants was observed among patients who required ETI, with a median age of 12 months. A significant difference in the ROX index was found from two hours onwards with cutoff points on the AUROC curve above 0.5. Conclusion: It was determined that the ROX Index can be used as a complementary tool to strengthen decision-making in pediatrics.
| Published in | American Journal of Pediatrics (Volume 10, Issue 2) |
| DOI | 10.11648/j.ajp.20241002.17 |
| Page(s) | 96-106 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
High-Flow Oxygen Therapy, Predictors, ROX Index, Tool, Achievable, Endotracheal Intubation
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APA Style
Calderón-Salavarría, K., Barreiro-Casanova, J. (2024). Application of the Rox Index as a Predictor of Respiratory Failure in Pediatric Patients Receiving High-Flow Oxygen Therapy Support at the Roberto Gilbert Elizalde Hospital. American Journal of Pediatrics, 10(2), 96-106. https://doi.org/10.11648/j.ajp.20241002.17
ACS Style
Calderón-Salavarría, K.; Barreiro-Casanova, J. Application of the Rox Index as a Predictor of Respiratory Failure in Pediatric Patients Receiving High-Flow Oxygen Therapy Support at the Roberto Gilbert Elizalde Hospital. Am. J. Pediatr. 2024, 10(2), 96-106. doi: 10.11648/j.ajp.20241002.17
AMA Style
Calderón-Salavarría K, Barreiro-Casanova J. Application of the Rox Index as a Predictor of Respiratory Failure in Pediatric Patients Receiving High-Flow Oxygen Therapy Support at the Roberto Gilbert Elizalde Hospital. Am J Pediatr. 2024;10(2):96-106. doi: 10.11648/j.ajp.20241002.17
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Download@article{10.11648/j.ajp.20241002.17,
author = {Karla Calderón-Salavarría and Jimmy Barreiro-Casanova},
title = {Application of the Rox Index as a Predictor of Respiratory Failure in Pediatric Patients Receiving High-Flow Oxygen Therapy Support at the Roberto Gilbert Elizalde Hospital
},
journal = {American Journal of Pediatrics},
volume = {10},
number = {2},
pages = {96-106},
doi = {10.11648/j.ajp.20241002.17},
url = {https://doi.org/10.11648/j.ajp.20241002.17},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20241002.17},
abstract = {Background: High-flow oxygen therapy is an ideal treatment for managing respiratory failure. It avoids orotracheal intubation; however, some patients are refractory to this treatment. The ROX Index aims to detect early failure in high-flow oxygen therapy; nevertheless, its use has been poorly studied in pediatrics. Objective: To evaluate the applicability of the ROX Index as a tool to determine the failure of high-flow oxygen therapy in pediatric patients admitted to the Roberto Gilbert Hospital. Methodology: Observational, prospective, longitudinal cohort study with a descriptive approach including 209 patients between 1 month and 17 years old who required high-flow oxygen therapy within the first 24 hours. ROX Index measurements were taken at 2, 4, 6, 12, and 24 hours with follow-up to determine the outcome. Result: A total of 209 patients meeting the inclusion criteria were obtained; 27 (12.9%) required endotracheal intubation (ETI), and 182 (87%) received high-flow oxygen therapy (HFNC). A higher frequency of younger infants was observed among patients who required ETI, with a median age of 12 months. A significant difference in the ROX index was found from two hours onwards with cutoff points on the AUROC curve above 0.5. Conclusion: It was determined that the ROX Index can be used as a complementary tool to strengthen decision-making in pediatrics.
},
year = {2024}
}
TY - JOUR T1 - Application of the Rox Index as a Predictor of Respiratory Failure in Pediatric Patients Receiving High-Flow Oxygen Therapy Support at the Roberto Gilbert Elizalde Hospital AU - Karla Calderón-Salavarría AU - Jimmy Barreiro-Casanova Y1 - 2024/05/30 PY - 2024 N1 - https://doi.org/10.11648/j.ajp.20241002.17 DO - 10.11648/j.ajp.20241002.17 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 96 EP - 106 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20241002.17 AB - Background: High-flow oxygen therapy is an ideal treatment for managing respiratory failure. It avoids orotracheal intubation; however, some patients are refractory to this treatment. The ROX Index aims to detect early failure in high-flow oxygen therapy; nevertheless, its use has been poorly studied in pediatrics. Objective: To evaluate the applicability of the ROX Index as a tool to determine the failure of high-flow oxygen therapy in pediatric patients admitted to the Roberto Gilbert Hospital. Methodology: Observational, prospective, longitudinal cohort study with a descriptive approach including 209 patients between 1 month and 17 years old who required high-flow oxygen therapy within the first 24 hours. ROX Index measurements were taken at 2, 4, 6, 12, and 24 hours with follow-up to determine the outcome. Result: A total of 209 patients meeting the inclusion criteria were obtained; 27 (12.9%) required endotracheal intubation (ETI), and 182 (87%) received high-flow oxygen therapy (HFNC). A higher frequency of younger infants was observed among patients who required ETI, with a median age of 12 months. A significant difference in the ROX index was found from two hours onwards with cutoff points on the AUROC curve above 0.5. Conclusion: It was determined that the ROX Index can be used as a complementary tool to strengthen decision-making in pediatrics. VL - 10 IS - 2 ER -
Pediatric Emergency Department, Roberto Gilbert Elizalde Children's Hospital, Guayaquil, Ecuador; School of Medicine, Santiago of Guayaquil Catholic University, Guayaquil, Ecuador
